RAFT Pharmaceuticals

biologics to treat chronic pain, neuroinflammation ... and beyond

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About Us

Raft Pharmaceuticals is a startup biopharmaceutical company developing novel therapy targeting lipid rafts in inflamed and activated cells. Raft’s product, recombinant protein RFT-001 regulates cholesterol trafficking in the plasma membrane and normalizes clustered and cholesterol-overloaded lipid raft microdomains – specifically in inflamed glia and macrophages, relevant to the development of chronic pain states. Chronic pain is a major health problem affecting 20% of the population and 40% of older adults, having an extraordinary negative impact on quality of life. The annual cost of chronic pain is $635B. Opiates, NSAIDs, and anticonvulsants relieve pain for short intervals, but are less effective for chronic therapy, have serious side effects and potential for diversion and addiction (opioid epidemics). Animal testing shows the unprecedented efficacy of RFT-001 in models of chemotherapy- and nerve injury-induced neuropathic pain, as well as migraine.  

team

Yury Miller, co-founder

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Professor of Medicine at UC San Diego

Broad expertise in cholesterol metabolism and cellular 

mechanisms of inflammation

Discovered a new mechanism linking cholesterol and inflammation

Tony Yaksh, co-founder

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Distinguished Professor of Anesthesiology at UC San Diego

Strong focus on spinal mechanisms of pain and analgesia

Significant experience in preclinical studies, performing pivotal 

small and large animal trials

Kevin Bacon, CEO

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PhD in Pharmacology

Over 30 years of drug discovery & development  expertise

Wealth of experience in pre-clinical and early-clinical 

research and development

Graham Beaton, COO

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PhD in Chemistry

Over 30 years experience in biotech and pharma

Compound discovery & development through IND

and early clinical trials

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RAFT Pharmaceuticals

10225 Barnes Canyon Rd, San Diego, CA 92121, USA